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Evaluation of drug resistance to doxorubicin in MCF-7 breast cancer cell line as a result of insulin treatment

P Kheradmand; S Vallian; S Esmaeili Mahani

Volume 9, Issue 4 , February 2019, , Pages 353-359

https://doi.org/10.52547/JCT.9.4.353

Abstract
  - Aim:In this study, the effect of insulin was investigated in induction of drug resistance to doxorubicin in MCF-7 breast cancer cell line. Material and method: MCF-7 cells were pretreated with 10 nM insulin for 48 and 72 hours, respectively. Then, different doses of doxorubicin (1, 5 and 10 μM) ...  Read More