Influence of Occupational Exposures on Sperm Parameters and Chromatin Structure
Volume 8, Issue 1, Summer 2017, Pages 52-68
https://doi.org/10.52547/JCT.8.1.52
L Babakhah, i L Azad, M Arbabian, M Tavalaee, M Bahadorani, MH Nasr- Esfahani
Abstract Aim: This study examines the sperm parameters (concentration, mobility and morphology) and the state of sperm DNA in infertile men exposed to various occupational exposures.
Material and Methods: This study was performed on 152 men who referred to Isfahan Fertility and Infertility Center )spring 2014 to autumn 2016( for diagnostic purposes. After an interview with all the participants, their semen samples were collected for assessment of sperm parameters and sperm chromatin health, based on the WHO protocol and the TUNEL method, respectively.
Results: The results showed that in men with prolonged sitting, high physiological activity and with exposure to chemical compounds, they had lower sperm motility and higher sperm DNA damage than the presented criteria by previous studies. In addition, in men with DNA damage higher than 10%, there was a significant decrease in sperm parameters.
Conclusion: Occupational exposure has negative effects on sperm parameters and sperm chromatin health, but more studies are needed to prove these results.